Medicine

Hibernation scientific research harnessed to handle obesity as well as change metabolism

.Attributes Medication, Released online: 04 September 2024 doi:10.1038/ s41591-024-03226-wBy underst...

CAR- T as well as mobile gene therapies are too expensive

.Mother Nature Medicine, Published online: 04 September 2024 doi:10.1038/ s41591-024-03231-zPoint-of...

The that genomics program of work with equitable execution of human genomics for worldwide health

.The publication of the initial draft of the individual genome series in 20011 was actually complied...

A time-stratified, case\u00e2 $ \"crossover research study of warmth direct exposure and perinatal death coming from 16 hospitals in sub-Saharan Africa

.Amongst 138,015 hospital-based singleton childbirths in 4 sub-Saharan African nations, our experts ...

Advancing international antibiotic investigation, progression and also get access to #.\n\nMurray, C. J. L. et cetera. International problem of microbial antimicrobial resistance in 2019: a step-by-step study. Lancet 399, 629\u00e2 $ \"655 (2022 ). AMR Frontrunnerses. Towards specific devotions and also action in the response to antimicrobial protection. Global Frontrunners Team on Antimicrobial Protection https:\/\/www.amrleaders.org\/resources\/m\/item\/glg-report (4 April 2024). World Wellness Association. That publishes listing of micro-organisms for which brand new prescription antibiotics are actually urgently required. Planet Health Institution https:\/\/www.who.int\/news\/item\/27-02-2017-who-publishes-list-of-bacteria-for-which-new-antibiotics-are-urgently-needed (27 February 2017). Globe Health Organization. WHO bacterial priority pathogens checklist, 2024: bacterial microorganisms of public health relevance to lead study, growth and methods to prevent and control antimicrobial protection. Planet Wellness Organization https:\/\/www.who.int\/publications\/i\/item\/9789240093461 (17 May 2024). Silver, L. L. A Gestalt approach to Gram-negative entry. Bioorg. Medication. Chem. 24, 6379\u00e2 $ \"6389 (2016 ). Article\u00c2.\nCAS\u00c2.\nPubMed\u00c2.\n\nGoogle Scholar\u00c2.\nSundqvist, M. Reversibility of antibiotic resistance. Ups. J. Medication. Sci. 119, 142\u00e2 $ \"148 (2014 ).\nGoogle Scholar\u00c2.\nPlanet Health And Wellness Organization. 2023 antibacterial agents in professional as well as preclinical progression: a summary and also review. Planet Health Company https:\/\/www.who.int\/publications\/i\/item\/9789240094000 (14 June 2024). O' Neill, J. et cetera. AMR Review. May 19, 2016 \u00e2 $\" Handling drug-resistant diseases internationally: last report as well as referrals. Assessment on Antimicrobial Resistance https:\/\/amr-review.org\/Publications.html (19 May 2016). Drive-AB Consortium. DRIVE-AB outcomes: reports and instruction. Steer AB https:\/\/drive-ab.eu\/drive-ab-outputs\/drive-ab-reports\/ (2016 ). Stern, S. et al. Appearing the wall surface: a call for collective action on antibiotics trial and error. Boston ma Consulting Team https:\/\/www.bundesgesundheitsministerium.de\/fileadmin\/Dateien\/5_Publikationen\/Gesundheit\/Berichte\/GUARD_Follow_Up_Report_Full_Report_final.pdf (February, 2017). Anderson, M., Panteli, D. &amp Mossialos, E. Plan Brief 51: How can the EU help sustainable advancement and accessibility to helpful antibiotics? plan options for existing and also new medicines. European Observatory on Health And Wellness Equipments and Policies https:\/\/eurohealthobservatory.who.int\/publications\/i\/how-can-the-eu-support-sustainable-innovation-and-access-to-effective-antibiotics-policy-options-for-existing-and-new-medicines (21 June 2023). Turnidge, J. &amp Christiansen, K. Prescription antibiotic use as well as resistance\u00e2 $\" proving the apparent. Lancet 365, 548\u00e2 $ \"549 (2005 ). Article\u00c2.\nPubMed\u00c2.\n\nGoogle Scholar\u00c2.\nGlobe Health Company. 2021 Mindful classification. WHO gain access to, view, get, classification of antibiotics for assessment and also surveillance of utilization. World Health Association https:\/\/www.who.int\/publications\/i\/item\/2021-aware-classification (30 September 2021). European Facility for Condition Prevention and Management. Antimicrobial resistance targets: exactly how can our experts reach all of them by 2030? ECDC https:\/\/www.ecdc.europa.eu\/sites\/default\/files\/documents\/amr-brief-eaad-2023-update.pdf (2023 ). Globe Wellness Organization. Shortage of advancement readied to undermine antibiotic functionality as well as wellness gains. Planet Health Institution https:\/\/www.who.int\/news\/item\/22-06-2022-22-06-2022-lack-of-innovation-set-to-undermine-antibiotic-performance-and-health-gains (22 June 2022). Magnano San, L. R. et cetera. Just how antimicrobial protection is actually linked to environment improvement: a review of 2 intertwined global difficulties. Int. J. Environ. Res. Hygienics 20, 1681 (2023 ). Article\u00c2.\n\nGoogle.com Scholar\u00c2.\nDolecek, C., Shakoor, S., Basnyat, B., Okwor, T. &amp Sartorius, B. Drug-resistant microbial contaminations: our experts require immediate activity and expenditure that concentrate on the weakest hyperlink. PLoS Biol. 20, e3001903 (2022 ). Article\u00c2.\nCAS\u00c2.\nPubMed\u00c2.\nPubMed Central\u00c2.\n\nGoogle.com Scholar\u00c2.\nPlanet Wellness Organization. Immunization protection. Planet Health Institution https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/immunization-coverage (15 July 2024). Chimhini, G., Magwenzi, M. &amp Fitzgerald, F. C. Contamination avoidance and management in low-resource setups: the need for the neighborhood, the contextual and also the practical. Contaminate. Prev. Pract. 4, 100135 (2022 ). Article\u00c2.\nCAS\u00c2.\nPubMed\u00c2.\n\nGoogle Scholar\u00c2.\nNour, S., Stokle, E., Ashiru-Oredope, D. &amp Wesangulae, E. Problems of carrying out antimicrobial conservation devices in reduced to center profit nations (LMICs). Infect. Prev. Pract. 5, 100315 (2023 ). Article\u00c2.\n\nGoogle Scholar\u00c2.\nAminov, R. A short past of the antibiotic period: trainings discovered as well as obstacles for the future. Front. Microbiol. 1, 134 (2010 ). Article\u00c2.\nPubMed\u00c2.\nPubMed Central\u00c2.\n\nGoogle.com Scholar\u00c2.\nOutterson, K. et al. Patient gain access to in 14 high-income countries to new antibacterials approved by the US Food and Drug Administration, European Medicines Organization, Japanese Pharmaceuticals and also Medical Devices Organization, or even Health And Wellness Canada, 2010\u00e2 $ \"2020. Clin. Contaminate. Dis. 74, 1183\u00e2 $ \"1190 (2022 ). Article\u00c2.\nPubMed\u00c2.\n\nGoogle.com Scholar\u00c2.\nGlobe Wellness Institution. 2021 antibacterial representatives in professional as well as preclinical advancement: a review and evaluation. World Wellness Company https:\/\/www.who.int\/publications\/i\/item\/9789240047655 (27 May 2022). Anti-biotics: the economics must sustain the scientific research. Nature 625, 7 (2024 ). Thomas, D. &amp Wessel, C. The state of advancement in antibacterial therapies. Medical Advancement Company https:\/\/www.bio.org\/sites\/default\/files\/2022-02\/The-State-of-Innovation-in-Antibacterial-Therapeutics.pdf (February, 2022). Strich, J. et al. Analyzing medical professional use of next-generation anti-biotics against immune Gram-negative diseases in U.S. medical centers: a retrospective pal research. Ann. Intern. Med. 177, 559\u00e2 $ \"572 (2024 ). Article\u00c2.\nPubMed\u00c2.\n\nGoogle Scholar\u00c2.\nThomas, D. &amp Wessel, C. The state of advancement in antibacterial therapeutics. Biotechnology Development Association https:\/\/www.bio.org\/sites\/default\/files\/2022-04\/BIO-Antibacterial-Report-2022.pdf (February 2022). Renwick, M. J., Brogan, D. M. &amp Mossialos, E. A methodical testimonial and essential analysis of reward approaches for exploration and also development of unique antibiotics. J. Antibiot. 69, 73\u00e2 $ \"88 (2016 ). Article\u00c2.\nCAS\u00c2.\n\nGoogle Scholar\u00c2.\nHealth And Wellness Urgent Preparedness as well as Action Authority. R &amp d of medical countermeasures. European Percentage https:\/\/health.ec.europa.eu\/health-emergency-preparedness-and-response-hera\/preparedness\/research-and-development-medical-countermeasures_en (2024 ). European Compensation. Pre-draft proposition for an European partnership under Horizon Europe One Health Antimicrobial Protection. European Percentage https:\/\/research-and-innovation.ec.europa.eu\/system\/files\/2022-02\/ec_rtd_he-partnerships-onehealth-amr.pdf (9 February 2022). Global Antibiotic Experimentation Partnership. Entasis Rehabs and the Worldwide Prescription Antibiotic Study &amp Growth Collaboration to build a brand-new procedure for gonorrhea. GARDP https:\/\/gardp.org\/entasis-therapeutics-and-the-global-antibiotic-research-development-partnership-to-develop-a-new-treatment-for-gonorrhea\/ (6 July 2017). Atal, I., Trinquart, L., Porcher, R. &amp Ravaud, P. Differential globalization of field- and also non-industry-sponsored professional tests. PLoS ONE 10, e0145122 (2015 ). Article\u00c2.\nPubMed\u00c2.\nPubMed Central\u00c2.\n\nGoogle Scholar\u00c2.\nGlobe Wellness Organization. Amount of medical trial registrations through area, illness, period of growth, age and sexual activity of test attendees (1999\u00e2 $ \"2022). Planet Health Company https:\/\/www.who.int\/observatories\/global-observatory-on-health-research-and-development\/monitoring\/number-of-trial-registrations-by-year-location-disease-and-phase-of-development (February 2023). Worldwide Prescription Antibiotic R &amp D Relationship. NeoSept1: a study to identify the ranking of existing as well as new prescription antibiotics mixtures to deal with newborns who remain in medical center along with intense sepsis. ISRCTN pc registry https:\/\/www.isrctn.com\/ISRCTN48721236 (17 January 2022). Public Health Organization of Canada. Federal government of Canada makes essential assets to overcome antimicrobial protection (AMR), Government of Canada https:\/\/www.canada.ca\/en\/public-health\/news\/2023\/05\/government-of-canada-makes-important-investment-to-fight-antimicrobial-resistance-amr.html (11 May 2023). Global Prescription Antibiotic Experimentation Relationship. Japan government backing supports GARDP\u00e2 $ s efforts to counter antibiotic protection. GARDP https:\/\/gardp.org\/japan-government-funding-supports-gardps-efforts-to-counter-antibiotic-resistance\/ (19 Oct 2023). Novo Nordisk Base. Novo Nordisk Structure companions with CARB-X to combat drug-resistant contaminations. novo nordisk base https:\/\/novonordiskfonden.dk\/en\/news\/novo-nordisk-foundation-partners-with-carb-x-to-fight-drug-resistant-infections\/ (9 January 2024). European Commission: European Wellness as well as Digital Manager Firm. Research study on bringing AMR medical countermeasures to the marketplace. Publications Office of the European Union https:\/\/op.europa.eu\/en\/publication-detail\/-\/publication\/51b2c82c-c21b-11ed-8912-01aa75ed71a1\/language-en (2023 ). Outterson, K. Predicting the suitable size of worldwide pull motivations for anti-bacterial medications. Wellness Aff. 40, 1758\u00e2 $ \"1765 (2021 ). Article\u00c2.\n\nGoogle Scholar\u00c2.\nEvans, E. J., Meyer, A. &amp Conti, R. M. Dimensions a market access reward for the growth of brand-new prescription antibiotics. Harvard Kennedy University https:\/\/www.hks.harvard.edu\/sites\/default\/files\/centers\/mrcbg\/Final_AWP_232.pdf (May 2024). Morel, C. M. et al. Market incentives as well as antibiotic protection: an intro to the antibiotic sensitivity bonus. J. Antibiot. 73, 421\u00e2 $ \"428 (2020 ). CAS\u00c2.\n\nGoogle.com Scholar\u00c2.\nBonnifield, R. &amp Towse, A. An enthusiastic USG progressed dedication for subscription-based investing in of unfamiliar antimicrobials and also its own expected roi. Center for Global Growth https:\/\/www.cgdev.org\/publication\/ambitious-usg-advanced-commitment-subscription-based-purchasing-novel-antimicrobials (15 Nov 2022). Towse, A. &amp Silverman Bonnifield, R. G7 investments in brand-new antibiotics would pay \u00e2 $\" for every person. Workplace of Health and wellness Business economics https:\/\/www.ohe.org\/insight\/g7-investments-in-new-antibiotics-would-pay-off-for-everyone\/ (9 December 2022). NHS England. NHS improves struggle versus lethal diseases adhering to productive world-first aviator. NHS England https:\/\/www.england.nhs.uk\/2023\/07\/nhs-steps-up-battle-against-life-threatening-infections-following-successful-world-first-pilot\/ (11 July 2023). US Congress. S. 1355 \u00e2 $\" PASTEUR Act of 2023. congress.gov www.congress.gov\/bill\/118th-congress\/senate-bill\/1355#:~:text=This%20bill%20authorizes%20the%20Department,and%20contains%20other%20related%20provisions (27 April 2023). International Commission. Reform of the EU pharmaceutical legalisation. European Commission https:\/\/health.ec.europa.eu\/medicinal-products\/pharmaceutical-strategy-europe\/reform-eu-pharmaceutical-legislation_en (26 April 2023). Gotham, D. et cetera. Repayment models to attack market breakdowns for antimicrobials: techniques absorbed France, Germany, Sweden, the United Kingdom, as well as the USA. Wellness Plan 125, 296\u00e2 $ \"306 (2020 ). Article\u00c2.\nPubMed\u00c2.\n\nGoogle.com Scholar\u00c2.\nInternational Alliance of Pharmaceutical Manufacturers as well as Associations. From protection to resilience: what could the future antibiotic pipeline seem like? IFMPA https:\/\/www.ifpma.org\/publications\/from-resistance-to-resilience-what-could-the-future-antibiotic-pipeline-look-like\/ (14 May 2024). International AMR R&ampD Center &amp Planet Health Company. Incentivising the growth of new anti-bacterial procedures: 2023 report card due to the Global AMR R&ampD Center and That. Worldwide AMR R&ampD Hub https:\/\/globalamrhub.org\/publications\/incentivising-the-development-of-new-antibacterial-treatments-2023\/ (2023 ). Glover, R. E., Singer, A., Roberts, A. P. &amp Kirchhelle, C. Why is the UK subscription design for anti-biotics looked at productive? Lancet Germ 4, e852\u00e2 $ \"e853 (2023 ). Article\u00c2.\nPubMed\u00c2.\n\nGoogle.com Scholar\u00c2.\nNon-paper \u00e2 $\" unique stimulations for the progression and going on the marketplace of antimicrobials. Politician https:\/\/www.politico.eu\/wp-content\/uploads\/2022\/12\/01\/Non-paper-Transferable-exclusivity-voucher-for-AMR-2.pdf (2022 ). Liu, L. et cetera. Global, regional, as well as nationwide causes of little one mortality in 2000\u00e2 $ \"13, with estimates to notify post-2015 priorities: an upgraded methodical analysis. Lancet 385, 430\u00e2 $ \"440 (2015 ). Article\u00c2.\nPubMed\u00c2.\n\nGoogle Scholar\u00c2.\nQuadri, F. et cetera. Antibacterial medicine scarcities from 2001 to 2013: ramifications for professional application. Clin. Corrupt. Dis. 60, 1737\u00e2 $ \"1742 (2015 ). Article\u00c2.\nPubMed\u00c2.\n\nGoogle Scholar\u00c2.\nBenhabib, A. et cetera. The French coverage system for medication lacks: summary and also trends coming from 2012 to 2018: an empirical retrospective research. BMJ Open 10, e034033 (2020 ). Article\u00c2.\nPubMed\u00c2.\nPubMed Central\u00c2.\n\nGoogle Scholar\u00c2.\nKlein, E. Y. et cetera. Assessment of that antibiotic intake and also accessibility targets in 76 countries, 2000\u00e2 $ \"15: a study of pharmaceutical sales data. Lancet Infect. Dis. 21, 107\u00e2 $ \"115 (2021 ). Article\u00c2.\nPubMed\u00c2.\n\nGoogle Scholar\u00c2.\nPyzik, O. Z. &amp Abubakar, I. Dealing with the phonies: handling second-rate as well as falsified medicines. Nat. Rev. Dis. Primers 8, 55 (2022 ). Hayhoe, B., Greenfield, G. &amp Majeed, A. Is it obtaining much easier to acquire anti-biotics in the UK? Br. J. Gen. Pract. 69, 54\u00e2 $ \"55 (2019 ). Article\u00c2.\nPubMed\u00c2.\nPubMed Central\u00c2.\n\nGoogle Scholar\u00c2.\nBlack Society for Laboratory Medication. Policy concise and infographics on antimicrobial protection (AMR) in Africa. ASLM https:\/\/aslm.org\/resource\/policy-brief-and-infographics-on-antimicrobial-resistance-amr-in-africa\/ (14 September 2022). Kanu, J. S. et cetera. National antibiotic consumption for individual usage in Sierra Leone (2017\u00e2 $ \"2019): a cross-sectional research study. Trop. Med. Infect. Dis. 6, 77 (2021 ). Article\u00c2.\nPubMed\u00c2.\nPubMed Central\u00c2.\n\nGoogle Scholar\u00c2.\nNamugambe, J. S. et al. National antimicrobial usage: evaluation of central storehouses materials to in-patient care health and wellness establishments coming from 2017 to 2019 in Uganda. Trop. Med. Contaminate. Dis. 6, 83 (2021 ).\nGoogle.com Scholar\u00c2.\nRobertson, J. et al. Variations in the consumption of antimicrobial medications in the International area, 2014\u00e2 $ \"2018: lookings for and also implications coming from ESAC-Net as well as That Europe. Front end. Pharmacol. 12, 639207 (2021 ). Article\u00c2.\nCAS\u00c2.\nPubMed\u00c2.\nPubMed Central\u00c2.\n\nGoogle Scholar\u00c2.\nShukar, S. et al. Medication lack: sources, impact, and also relief approaches. Front end. Pharmacol. 12, 693426 (2021 ). Article\u00c2.\nCAS\u00c2.\nPubMed\u00c2.\nPubMed Central\u00c2.\n\nGoogle.com Scholar\u00c2.\nOutterson, K., Orubu, E. S. F., Rex, J., \u00c3 ... rdal, C. &amp Zaman, M. H. Client access in 14 high-income countries to brand new antibacterials authorized due to the United States Food and Drug Administration, European Medicines Company, Japanese Pharmaceuticals and Medical Tools Firm, or Health Canada, 2010\u00e2 $ \"2020. Clin. Affect. Dis. 74, 1183\u00e2 $ \"1190 (2021 ). Article\u00c2.\nPubMed Central\u00c2.\n\nGoogle Scholar\u00c2.\nPulcini, C. et al. Wasted anti-biotics: a follow-up stock research study in Europe, the U.S.A., Canada as well as Australia. Int. J. Antimicrob. Brokers 49, 98\u00e2 $ \"101 (2017 ). Article\u00c2.\nCAS\u00c2.\nPubMed\u00c2.\n\nGoogle.com Scholar\u00c2.\nRottingen, J. A. &amp Farrar, J. Targeted wellness technology for international wellness. Br. Med. J. 366, 15601 (2019 ).\nGoogle.com Scholar\u00c2.\nAMR Industry Alliance. The 2023 AMR Industry Alliance progress survey: manufacturing and the environment. amr Business Collaboration https:\/\/www.amrindustryalliance.org\/wp-content\/uploads\/2023\/12\/AMRIA_Manufacturing-and-the-environment-FINAL.pdf (2023 ). Munoz, V., Visentin, F., Invasion, D. &amp Gaule, P. Can clinical products be developed on a charitable manner? Looking into product growth collaborations for neglected health conditions. Sci. Public law 42, 315\u00e2 $ \"338 (2015 ). Article\u00c2.\n\nGoogle Scholar\u00c2.\nSwaminathan, S. et al. Reboot biomedical R&ampD in the worldwide social passion. Attributes 602, 207\u00e2 $ \"210 (2022 ). Article\u00c2.\nCAS\u00c2.\nPubMed\u00c2.\n\nGoogle.com Scholar\u00c2.\nAfrica Centres for Illness Control and Protection. Africa CDC initiates strong relocate to get Africa\u00e2 $ s health future through developing a 50 billion dollar clinical market. AfricaCDC https:\/\/africacdc.org\/news-item\/africa-cdc-spearheads-bold-move-to-secure-africas-health-future-by-creating-a-50-billion-dollar-medical-market\/ (19 February 2024). Gore, C., Morin, S., R\u00c3 \u00b8 ttingen, J. A. &amp Kieny, M. P. Haggling public-health intellectual property licensing deals to improve accessibility to health innovations: an insider\u00e2 $ s tale. BMJ Chunk. Wellness 8, e012964 (2023 ). Article\u00c2.\nPubMed\u00c2.\nPubMed Central\u00c2.\n\nGoogle Scholar\u00c2.\nSuleman, F., Low, M., Moon, S. &amp Morgan, S. G. New company styles for research and development with affordability criteria are needed to have to achieve fair costs of medicines. Br. Medication. J. 368, l4408 (2020 ). Article\u00c2.\n\nGoogle Scholar\u00c2.\nCombating Antibiotic-Resistant Micro-organisms Biopharmaceutical Accelerator. Stewardship as well as gain access to. CARB-X https:\/\/carb-x.org\/about\/stewardship-and-access\/ (2024 ). Worldwide Anti-biotic Experimentation Relationship. Shinogi, GARDP and also CHAI announce spots permit as well as partnership contracts to manage bacterial contaminations by growing accessibility to cefiderocol in 135 countries. GARDP https:\/\/gardp.org\/shionogi-gardp-and-chai-announce-landmark-license-and-collaboration-agreements-to-treat-bacterial-infections-by-expanding-access-to-cefiderocol-in-135-countries\/ (15 June 2022). AMR Business Partnership. Leaving the laboratory: tracking the decrease in AMR R&ampD professionals. amr Field Partnership https:\/\/www.amrindustryalliance.org\/wp-content\/uploads\/2023\/02\/Leaving-the-Lab_final-1.pdf (February, 2024). G7 Wellness Ministers. G7 Wellness Ministers\u00e2 $ Communiqu\u00c3 \u00a9. G7 Germany www.g7germany.de\/resource\/blob\/974430\/2042058\/5651daa321517b089cdccfaffd1e37a1\/2022-05-20-g7-health-ministers-communique-data.pdf (twenty May 2022). G20. G20 contact us to activity on antimicrobial resistance. G7G20 Records Data bank https:\/\/g7g20-documents.org\/database\/document\/2022-g20-indonesia-sherpa-track-health-ministers-ministers-annex-g20-call-to-action-on-antimicrobial-resistance (28 October 2022). Global Coalition on Aging &amp Transmittable Diseases Society of America. 2024 AMR preparedness index progress report. Gauging government action on AMR policy. Global Union on Growing old https:\/\/globalcoalitiononaging.com\/wp-content\/uploads\/2024\/01\/2024-AMR-Index-Progress-Report.pdf (2024 ). Food and also Horticulture Organization of the United Nations, United Nations Environment Programme, Globe Wellness Institution &amp. Globe Company for Creature Health And Wellness. International data source for tracking antimicrobial resistance (AMR): country self-assessment poll (TrACSS). That https:\/\/amrcountryprogress.org\/

/map-viewindicator2.3 (2023 ). Van Katwyk, S. R. &amp Outterson K. Introduction: AMR belongs in the ...

Integrating liver endpoints in professional trials of heart and also kidney health condition

.Attributes Medication, Posted online: 03 September 2024 doi:10.1038/ s41591-024-03223-zThis Perspec...

FALSE:: MISTAKE: UNSUPPORTED ENCODING...

Artificial intelligence assisted screening for cardiomyopathies in an obstetric populace: a pragmatic randomized scientific trial

.Test design and also oversightThe Screening process for PEripartum Cardiomyopathies along with Expe...

Sustained HIV remission after allogeneic hematopoietic stem tissue transplant along with wild-type CCR5 benefactor tissues

.Attributes Medicine, Released online: 02 September 2024 doi:10.1038/ s41591-024-03277-zHIV remissio...

Senolytics target cellular senescence-- however can they slow down aging?

.In the 1960s, US anatomist Leonard Hayflick observed that replicative cells possess a limited amoun...